2015 American Heart Association (AHA) Advanced Cardiac Life Support (ACLS) Changes
2015 ACLS Summary of Key Issues and Major Changes Vasopressors for Resuscitation : Vasopressin 2015 ( Updated ) : Vasopressin in combination with epinephrine offers no advantage as a substitute for standard-dose epinephrine in cardiac arrest. 2010 ( Old ): One dose of vasopressin 40 units IV/ intraosseously may replace either the first or second dose of epinephrine in the treatment of cardiac arrest. Why: Both epinephrine and vasopressin administration during cardiac arrest have been shown to improve ROSC. Review of the available evidence shows that efficacy of the 2 drugs is similar and that there is no demonstrable benefit from administering both epinephrine and vasopressin as compared with epinephrine alone. In the interest of simplicity, vasopressin has been removed from the Adult Cardiac Arrest Algorithm. ETCO2 for Prediction of Failed Resuscitation 2015 ( New ): In intubated patients, failure to achieve an ETCO2 of greater than 10 mm Hg by waveform capnog...